Canadian Burden of Skin Disease From 1990 to 2017: Results From the Global Burden of Disease 2017 Study

Alanna C Bridgman¹, Christina Fitzmaurice^{2

3

4}, Robert P Dellavalle^{5

6

7}, Chante Karimkhani Aksut^{6

7}, Ayman Grada⁸, Mohsen Naghavi², Navid Manafi^{9

10}, Andrew T Olagunju^{11

12}, Tinuke O Olagunju¹³, Ranjani Somayaji^{14

15}, Aaron M Drucker^{16

17}

Affiliations

¹ 4257 School of Medicine, Queen's University, Kingston, ON, Canada.
² 7284 Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
³ Division of Hematology, University of Washington, Seattle, WA, USA.
⁴ Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, WA, USA.
⁵ 12226 School of Medicine, University of Colorado Denver, Aurora, CO, USA.
⁶ Dermatology Service, US Department of Veterans Affairs (VA), Denver, CO, USA.
⁷ 129263 Department of Dermatology, University of Colorado School of Medicine, Denver, CO.
⁸ 12259 School of Medicine, Boston University, Boston, MA, USA.
⁹ 440827 Ophthalmology Department, Iran University of Medical Sciences, Tehran, Iran.
¹⁰ Ophthalmology Department, University of Manitoba, Winnipeg, MB, Canada.
¹¹ 62703 Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
¹² Department of Psychiatry, University of Lagos, Lagos, Nigeria.
¹³ 62703 Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
¹⁴ 2129 Department of Medicine, University of Calgary, Calgary, AB, Canada.
¹⁵ Department of Medicine, University of Washington, Seattle, WA, USA.
¹⁶ Division of Dermatology, University of Toronto, Toronto, ON, Canada.
¹⁷ 7985 Women's College Research Institute, Women's College Hospital, Toronto, ON, Canada.

PMID: 31994902
PMCID: PMC7109598
DOI: 10.1177/1203475420902047

Canadian Burden of Skin Disease From 1990 to 2017: Results From the Global Burden of Disease 2017 Study

Alanna C Bridgman et al. J Cutan Med Surg. 2020 Mar/Apr.

. 2020 Mar/Apr;24(2):161-173.

doi: 10.1177/1203475420902047. Epub 2020 Jan 29.

Authors

Affiliations

¹ 4257 School of Medicine, Queen's University, Kingston, ON, Canada.
² 7284 Institute for Health Metrics and Evaluation, University of Washington, Seattle, WA, USA.
³ Division of Hematology, University of Washington, Seattle, WA, USA.
⁴ Department of Health Metrics Sciences, School of Medicine, University of Washington, Seattle, WA, USA.
⁵ 12226 School of Medicine, University of Colorado Denver, Aurora, CO, USA.
⁶ Dermatology Service, US Department of Veterans Affairs (VA), Denver, CO, USA.
⁷ 129263 Department of Dermatology, University of Colorado School of Medicine, Denver, CO.
⁸ 12259 School of Medicine, Boston University, Boston, MA, USA.
⁹ 440827 Ophthalmology Department, Iran University of Medical Sciences, Tehran, Iran.
¹⁰ Ophthalmology Department, University of Manitoba, Winnipeg, MB, Canada.
¹¹ 62703 Department of Psychiatry and Behavioural Neurosciences, McMaster University, Hamilton, ON, Canada.
¹² Department of Psychiatry, University of Lagos, Lagos, Nigeria.
¹³ 62703 Department of Pathology and Molecular Medicine, McMaster University, Hamilton, ON, Canada.
¹⁴ 2129 Department of Medicine, University of Calgary, Calgary, AB, Canada.
¹⁵ Department of Medicine, University of Washington, Seattle, WA, USA.
¹⁶ Division of Dermatology, University of Toronto, Toronto, ON, Canada.
¹⁷ 7985 Women's College Research Institute, Women's College Hospital, Toronto, ON, Canada.

PMID: 31994902
PMCID: PMC7109598
DOI: 10.1177/1203475420902047

Abstract

Background: Skin diseases can have high morbidity that can be costly to society and individuals. To date, there has been no comprehensive assessment of the burden of skin disease in Canada.

Objectives: To evaluate the burden of 18 skin and subcutaneous diseases from 1990 to 2017 in Canada using the Global Burden of Disease (GBD) data.

Methods: The 2017 GBD study measures health loss from 359 diseases and injuries in 195 countries; we evaluated trends in population health in Canada from 1990 to 2017 using incidence, prevalence, mortality, years of life lost (YLLs), years lived with disability (YLDs), and disability-adjusted life years (DALYs). Data are presented as rates (per 100 000), counts, or percent change with the uncertainty interval in brackets.

Results: From 1990 to 2017 for all skin diseases, DALY rates increased by 8% to 971 per 100 000 (674-1319), YLD rates increased by 8% to 897 per 100 000 (616-1235), YLL rates increased by 4% to 74 per 100 000 (53-89), and death rates increased by 18% to 5 per 100 000 (3-6). DALY rates for melanoma increased by 2% to 54 per 100 000 (39-68), for keratinocyte carcinoma by 14% to 17 per 100 000 (16-19), and for skin and subcutaneous disease by 8% to 900 per 100 000 (619-1233). The observed over expected ratios were higher for skin and subcutaneous disease (1.37) and keratinocyte carcinoma (1.17) and were lower for melanoma (0.73).

Conclusions: The burden of skin disease has increased in Canada since 1990. These results can be used to guide health policy regarding skin disease in Canada.

Keywords: disability; incidence; prevalence; skin disease.

PubMed Disclaimer

Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared the following potential conflicts of interest with respect to the research, authorship, and/or publication of this article. In the last 3 years, Dr Drucker served as an investigator and has received research funding from Sanofi and Regeneron and has been a consultant for Sanofi, RTI Health Solutions, Eczema Society of Canada, and Canadian Agency for Drugs and Technology in Health. He has received honoraria from Prime Inc, Spire Learning, CME Outfitters, and Eczema Society of Canada. His institution receives education grants from Sanofi.

Figures

**Figure 1**
Disability-adjusted life year (DALY) rates (per 100 000) for 18 skin diseases in Canada in 2017. BCC, basal cell carcinoma; SCC, squamous cell carcinoma.

See this image and copyright information in PMC

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Canadian Burden of Skin Disease From 1990 to 2017: Results From the Global Burden of Disease 2017 Study

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Canadian Burden of Skin Disease From 1990 to 2017: Results From the Global Burden of Disease 2017 Study

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Conflict of interest statement

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