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. 1988 Oct;34(4):507-10.
doi: 10.1038/ki.1988.210.

Localization of the gene for X-linked Alport's syndrome

H Brunner  1 , C Schröder, C van Bennekom, E Lambermon, J Tuerlings, D Menzel, H Olbing, L Monnens, B Wieringa, H H Ropers
Affiliations
Free article

Localization of the gene for X-linked Alport's syndrome

H Brunner et al. Kidney Int. 1988 Oct.
Free article

Abstract

X-chromosomal DNA probes defining various polymorphic DNA markers were used to study genetic linkage in three families with Alport's syndrome. With the DXS17 marker, only a single cross-over was observed in 26 informative meioses, and evidence for linkage was also obtained with the DXS11 marker. These data localize the gene for the X-linked form of Alport's syndrome to the middle of the long arm of the X chromosome.

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