doi: 10.1038/ki.1988.210.
Localization of the gene for X-linked Alport's syndrome
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- PMID: 3199669
- DOI: 10.1038/ki.1988.210
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Localization of the gene for X-linked Alport's syndrome
Kidney Int.
1988 Oct.
Free article
Abstract
X-chromosomal DNA probes defining various polymorphic DNA markers were used to study genetic linkage in three families with Alport's syndrome. With the DXS17 marker, only a single cross-over was observed in 26 informative meioses, and evidence for linkage was also obtained with the DXS11 marker. These data localize the gene for the X-linked form of Alport's syndrome to the middle of the long arm of the X chromosome.
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