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Review
. 2020 Jan 4:2020:8749564.
doi: 10.1155/2020/8749564. eCollection 2020.

Nonalcoholic Fatty Liver Disease: Pathogenesis and Treatment in Traditional Chinese Medicine and Western Medicine

Tingting Shi  1 , Li Wu  2 , Wenjun Ma  1 , Liping Ju  1 , Minghui Bai  1 , Xiaowei Chen  1 , Shourong Liu  1 , Xingxin Yang  3 , Junping Shi  4
Affiliations
Review

Nonalcoholic Fatty Liver Disease: Pathogenesis and Treatment in Traditional Chinese Medicine and Western Medicine

Tingting Shi et al. Evid Based Complement Alternat Med. .

Abstract

Nonalcoholic Fatty Liver Disease (NAFLD) is one of the most important causes of liver disease worldwide and probably destined to become the leading cause of end-stage liver disease in the coming decades, affecting both adults and children. Faced with the severe challenges for the prevention and control of NAFLD, this article discusses the understanding and mechanism of NAFLD from Chinese and Western medicine. Moreover, the progress regarding its treatment in both Chinese and Western medicine is also summarized. Both Chinese medicine and Western medicine have their own characteristics and clinical efficacy advantages in treating diseases. The purpose of this article is to hope that Chinese and Western medicine have complementary advantages, complementing each other to improve clinical NAFLD therapy prevention and treatment methods to receive more and more attention throughout the global medical community.

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Conflict of interest statement

The authors declare that there are no conflicts of interest associated with this manuscript.

Figures

Figure 1
Figure 1
Six Chinese traditional medicine herbs. (a) Hawthorn. (b) Salvia miltiorrhiza. (c) Rhizoma alismatis. (d) Radix bupleuri. (e) Polygonum multiflorum. (f) Red yeast rice.
Figure 2
Figure 2
Chemical structure of antioxidant compounds discussed in the text. (a) N-acetylcysteine. (b) Polyene phosphatidylcholine. (c) Vitamin E. (d) Silymarin.
Figure 3
Figure 3
Scheme of the general mechanism of antioxidants on NAFLD. NAFL: nonalcoholic fatty liver; NASH: nonalcoholic steatohepatitis; T2D: type 2 diabetes; FFA: free fatty acids; DAG: diacylglycerol; TG: triglycerides; ox stress: oxidative stress.
See this image and copyright information in PMC

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