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Case Reports
. 2019 Dec 11;8(1):86-91.
doi: 10.1002/ccr3.2569. eCollection 2020 Jan.

ALS or ALS mimic by neuroborreliosis-A case report

Affiliations
Case Reports

ALS or ALS mimic by neuroborreliosis-A case report

Isabelle Wirsching et al. Clin Case Rep. .

Abstract

Comprehensive investigation in motor neuron disease is vital not to miss a treatable differential diagnosis. Neuroborreliosis should be considered during an ALS work-up. However, false-positive CSF results do occur, and thus, results should be interpreted carefully in context of all clinical test results.

Keywords: ALS mimic; El Escorial; motor neuron disease; muscle atrophy; neuroborreliosis.

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Conflict of interest statement

None of the authors has any conflict of interest to disclose.

Figures

Figure 1
Figure 1
Excerpt from the electromyographic recording of the left first dorsal interosseous muscle. Fibrillations (arrows) and sporadic positive sharp waves (arrow heads) are seen

References

    1. Agah E, Saleh F, Sanjari Moghaddam H, Saghazadeh A, Tafakhori A, Rezaei N. CSF and blood biomarkers in amyotrophic lateral sclerosis: protocol for a systematic review and meta‐analysis. Syst Rev. 2018;7(1):237. - PMC - PubMed
    1. Gendron TF, Chew J, Stankowski JN, et al. Poly(GP) proteins are a useful pharmacodynamic marker for C9ORF72‐associated amyotrophic lateral sclerosis. Sci Transl Med. 2017;9:383. - PMC - PubMed
    1. Johnsen B, Pugdahl K, Fuglsang‐Frederiksen A, et al. Diagnostic criteria for amyotrophic lateral sclerosis: a multicentre study of inter‐rater variation and sensitivity. Clin Neurophysiol. 2019;130(2):307‐314. - PubMed
    1. Ludolph A, Drory V, Hardiman O, et al. A revision of the El Escorial criteria ‐ 2015. Amyotroph Lateral Scler Frontotemporal Degener. 2015;16(5–6):291‐292. - PubMed
    1. de Carvalho M, Dengler R, Eisen A, et al. Electrodiagnostic criteria for diagnosis of ALS. Clin Neurophysiol. 2008;119(3):497‐503. - PubMed

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