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. 2019 Jun 25;9(3):28-33.
doi: 10.1093/af/vfz017. eCollection 2019 Jul.

Livestock animals to study infertility in women

Mohamed A Abedal-Majed  1 , Andrea S Cupp  2
Affiliations

Livestock animals to study infertility in women

Mohamed A Abedal-Majed et al. Anim Front. .
No abstract available

Keywords: follicles; human; infertility; livestock.

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Figures

Figure 1.
Figure 1.
Conceptual model of how androstenedione affects the normal hypothalamic–anterior pituitary–ovarian axis resulting in anovulation. A4, androstenedione; E2, estradiol-17β; FSH, follicle-stimulating hormone; GnRH, gonadotropin-releasing hormone; LH, luteinizing hormone.
Figure 2.
Figure 2.
Conceptual model of the normal hormonal steroidogenic pathway in theca cells of the bovine ovary. Cows with excess androstenedione (High A4) have increased expression of several gene (e.g., CYP11A1 and CYP17A1) in the steroidogenic pathway.
Figure 3.
Figure 3.
Stages of ovarian follicular development in bovine ovaries. Normal ovarian follicles develop from primordial follicles to primary follicles to secondary follicles to antral follicles, which may ovulate. In cows with excess androstenedione (High A4), secondary ovarian follicles do not develop to the antral follicle stage; thus, ovulation is blocked.
See this image and copyright information in PMC

References

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