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. 2019 Jun 25;9(3):52-59.
doi: 10.1093/af/vfz025. eCollection 2019 Jul.

A swine model of soy protein-induced food allergenicity: implications in human and swine nutrition

John Scott Radcliffe  1 , Luiz F Brito  1 , Lavanya Reddivari  2 , Monica Schmidt  3 , Eliot M Herman  3 , Allan P Schinckel  1
Affiliations

A swine model of soy protein-induced food allergenicity: implications in human and swine nutrition

John Scott Radcliffe et al. Anim Front. .
No abstract available

Keywords: allergy; soybeans; swine.

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Figures

Figure 1.
Figure 1.
Intestinal barrier function is maintained by a series of tight junction proteins, which connect adjacent cells and prevent bacteria and protein from traversing the paracellular space. Reductions in gut barrier function potentially allow bacteria and proteins to travel between cells. It has been hypothesized that reductions in gut barrier function may result in increased incidences of food allergy development. Conversely, food allergy development has also been reported to reduce gut barrier function.
Figure 2.
Figure 2.
The 2004 Food and Allergen Labeling Consumer Protection Act (FALCPA) regulated the inclusion of eight primary foods responsible for 90% of all documented food allergies by requiring clear identifiable labeling to assist consumers to avoid problematic foods. These eight allergens are milk, eggs, fish, shellfish (Crustaceans), tree nuts, peanuts, wheat, and soybeans.
Figure 3.
Figure 3.
(A) Classic wheal (swelling) and flare (redness) response following a skin allergy test in sensitized pigs selected for hypersensitivity to soy protein. (B) Whole body atopic rash in a soy hypersensitive pig following a soy skin allergy test.
See this image and copyright information in PMC

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