Vitamin D and obesity in adults: a pathophysiological and clinical update

Abstract

Vitamin D deficiency has become an increasing focus of clinical interest, especially in understanding its associations with obesity in adults. The pathological associations linking the two appear to demonstrate complex cellular inflammatory, hormonal and genetic pathways. Enhanced understanding at both microcellular and clinical levels will help clarify the role of obesity in the development of vitamin D deficiency.

Keywords: Adipocyte; Deficiency; Metabolism; Obesity; Pathogenesis; Vitamin D.