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Comment
. 2020 Mar 15;16(3):345-346.
doi: 10.5664/jcsm.8270. Epub 2020 Jan 14.

The collapsing anatomical structure is not always the primary site of flow limitation in obstructive sleep apnea

Affiliations
Comment

The collapsing anatomical structure is not always the primary site of flow limitation in obstructive sleep apnea

Guilherme J M Garcia et al. J Clin Sleep Med. .

Abstract

Garcia GJM, Woodson BT. The collapsing anatomical structure is not always the primary site of flow limitation in obstructive sleep apnea. J Clin Sleep Med. 2020;16(3):345–346.

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Figures

Figure 1
Figure 1. Diagram illustrating the concept that the site of flow limitation may be different from the site of airway collapse.
In a hypothetical patient, the nasal valve is the site of flow limitation, but the airway collapses at the soft palate and tongue. (A) In early inspiration most of the pressure drop occurs in the rigid nasal cavity due to a constriction at the nasal valve. (B) Once the local pressure falls below the buckling pressure of each anatomical structure, the airway collapses at that location, which further increases the pressure loss along the upper airway. Symbols: Patm = atmospheric pressure; Pb palate = buckling pressure of the soft palate; Pb tongue = buckling pressure of the tongue.

Comment on

References

    1. Yanagisawa-Minami A, Sugiyama T, Iwasaki T, Yamasaki Y. Primary site identification in children with obstructive sleep apnea by computational fluid dynamics analysis of the upper airway. J Clin Sleep Med. 2020;16(3):431–439. - PMC - PubMed
    1. Wootton DM, Luo H, Persak SC, et al. Computational fluid dynamics endpoints to characterize obstructive sleep apnea syndrome in children. J Appl Physiol. 2014;116(1):104–112. - PMC - PubMed
    1. Pirnar J, Dolenc-Grošelj L, Fajdiga I, Žun I. Computational fluid-structure interaction simulation of airflow in the human upper airway. J Biomech. 2015;48(13):3685–3691. - PubMed
    1. Liu Y, Mitchell J, Chen Y, Yim W, Chu W, Wang RC. Study of the upper airway of obstructive sleep apnea patient using fluid structure interaction. Respir Physiol Neurobiol. 2018;249:54–61. - PubMed
    1. Subramaniam DR, Arens R, Wagshul ME, Sin S, Wootton DM, Gutmark EJ. Biomechanics of the soft-palate in sleep apnea patients with polycystic ovarian syndrome. J Biomech. 2018;76:8–15. - PMC - PubMed

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