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. 2020 Jan 31;9(1):275-277.
doi: 10.1080/22221751.2020.1723441. eCollection 2020.

An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies

Affiliations

An emerging coronavirus causing pneumonia outbreak in Wuhan, China: calling for developing therapeutic and prophylactic strategies

Shibo Jiang et al. Emerg Microbes Infect. .

Erratum in

  • Correction.
    Jiang S. Jiang S. Emerg Microbes Infect. 2020 Mar 5;9(1):539. doi: 10.1080/22221751.2020.1737363. eCollection 2020. Emerg Microbes Infect. 2020. PMID: 32134367 Free PMC article. No abstract available.
No abstract available

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Conflict of interest statement

No potential conflict of interest was reported by the author(s).

Figures

Figure 1.
Figure 1.
Analysis of the functional domains in 2019-nCoV spike protein and its gene. (A) Phylogenetic analysis of S gene of 2019-nCoV (Wuhan-Hu-1), bat-SL-CoVZXC21, bat-SL-CoVZXC45, SARS-CoV and other coronaviruses using Neighbor-Joining method. (B) The representative scheme of functional domains in S protein of 2019-nCoV. SP, signal peptide; NTD, N-terminal domain; RBD, receptor-binding domain; FP, fusion peptide, HR1, heptad repeat 1; HR2, heptad repeat 2; TM, transmembrane domain; CP, cytoplasmic domain. (C) The target sites in 2019-nCoV S for development of vaccines, antibodies and fusion/entry inhibitors.

References

    1. Lu H, Stratton CW, Tang YW.. Outbreak of pneumonia of unknown etiology in Wuhan China: the mystery and the miracle. J Med Virol. 2020;92. doi: 10.1002/jmv.25678 - DOI - PMC - PubMed
    1. Chan JF, Kok KH, Zhu Z, et al. . G enomic characterization of the 2019 novel human-pathogenic coronavirus isolated from patients with acute respiratory disease in Wuhan, Hubei, China. Emerg Microbes Infect. 2020;9:221–236. doi: 10.1080/22221751.2020.1719902 - DOI - PMC - PubMed
    1. Hu D, Zhu C, Ai L, et al. . G enomic characterization and infectivity of a novel SARS-like coronavirus in Chinese bats. Emerg Microbes Infect. 2018;7:154. - PMC - PubMed
    1. Zhang N, Wang L, Deng X, et al. . R ecent advances in the detection of respiratory virus infection in humans. J Med Virol. 2020;92. DOI:10.1002/jmv.25674 doi: 10.1002/jmv.25611 - DOI - DOI - PMC - PubMed
    1. Du L, He Y, Zhou Y, et al. . The spike protein of SARS-CoV—a target for vaccine and therapeutic development. Nat Rev Microbiol. 2009;7:226–236. doi: 10.1038/nrmicro2090 - DOI - PMC - PubMed

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