Is unrelated donor or haploidentical hematopoietic transplantation preferred for patients with acute myeloid leukemia in remission?

Affiliations

Editorial

Richard Champlin. Haematologica. 2020.

. 2020 Jan 31;105(2):252-254.

doi: 10.3324/haematol.2019.239624. Print 2020.

No abstract available

Comment on

Alternative donor transplantation for acute myeloid leukemia in patients aged ≥50 years: young HLA-matched unrelated or haploidentical donor?
Perales MA, Tomlinson B, Zhang MJ, St Martin A, Beitinjaneh A, Gibson J, Hogan W, Kekre N, Lazarus H, Marks D, McGuirk J, Romee R, Solh M, Wagner JE, Weisdorf DJ, de Lima M, Eapen M. Perales MA, et al. Haematologica. 2020 Jan 31;105(2):407-413. doi: 10.3324/haematol.2018.215202. Print 2020. Haematologica. 2020. PMID: 31101756 Free PMC article.

1. Perales MA, Tomlinson B, Zhang MJ, et al. Alternative donor transplantation for acute myeloid leukemia in patients aged ≥50 years: young HLA-matched unrelated or haploidentical Donor? Haematologica. 2019;105(2):407–413. - PMC - PubMed
1. Weisdorf DJ, Anasetti C, Antin JH, et al. Allogeneic bone marrow transplantation for chronic myelogenous leukemia: comparative analysis of unrelated versus matched sibling donor transplantation. Blood. 2002;99(6):1971–1977. - PubMed
1. Gupta V, Tallman MS, He W, et al. Comparable survival after HLA-well-matched unrelated or matched sibling donor transplantation for acute myeloid leukemia in first remission with unfavorable cytogenetics at diagnosis. Blood. 2010;116(11):1839–1848. - PMC - PubMed
1. Gragert L, Eapen M, Williams E, et al. HLA match likelihoods for hematopoietic stem-cell grafts in the U.S. registry. N Engl J Med. 2014;371(4):339–348. - PMC - PubMed
1. Kollman C, Spellman SR, Zhang MJ, et al. The effect of donor characteristics on survival after unrelated donor transplantation for hematologic malignancy. Blood. 2016;127(2):260–267. - PMC - PubMed