Technical comment on "Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis"

A J Salinger^{1

2}, M L Dubuke^{1

3}, C Carmona-Rivera⁴, A J Maurais, S A Shaffer^{1

3}, E Weerapana², P R Thompson⁵, M J Kaplan⁶

Affiliations

¹ Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
² Department of Chemistry, Boston College, Chestnut Hill, MA 02467, USA.
³ Mass Spectrometry Facility, University of Massachusetts Medical School, Shrewsbury, MA 01545, USA.
⁴ Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
⁵ Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Paul.Thompson@umassmed.edu mariana.kaplan@nih.gov.
⁶ Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Paul.Thompson@umassmed.edu mariana.kaplan@nih.gov.

Comment

A J Salinger et al. Sci Immunol. 2020.

. 2020 Jan 31;5(43):eaax5672.

doi: 10.1126/sciimmunol.aax5672.

A J Salinger^{1

2}, M L Dubuke^{1

3}, C Carmona-Rivera⁴, A J Maurais, S A Shaffer^{1

3}, E Weerapana², P R Thompson⁵, M J Kaplan⁶

¹ Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA.
² Department of Chemistry, Boston College, Chestnut Hill, MA 02467, USA.
³ Mass Spectrometry Facility, University of Massachusetts Medical School, Shrewsbury, MA 01545, USA.
⁴ Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA.
⁵ Department of Biochemistry and Molecular Pharmacology, University of Massachusetts Medical School, Worcester, MA 01605, USA. Paul.Thompson@umassmed.edu mariana.kaplan@nih.gov.
⁶ Systemic Autoimmunity Branch, National Institute of Arthritis and Musculoskeletal and Skin Diseases, National Institutes of Health, Bethesda, MD 20892, USA. Paul.Thompson@umassmed.edu mariana.kaplan@nih.gov.

Abstract

Reassessment of citrullinome cargo in neutrophil extracellular traps confirms the presence of citrullinated peptides.

Synovial fibroblast-neutrophil interactions promote pathogenic adaptive immunity in rheumatoid arthritis.
Carmona-Rivera C, Carlucci PM, Moore E, Lingampalli N, Uchtenhagen H, James E, Liu Y, Bicker KL, Wahamaa H, Hoffmann V, Catrina AI, Thompson P, Buckner JH, Robinson WH, Fox DA, Kaplan MJ. Carmona-Rivera C, et al. Sci Immunol. 2017 Apr;2(10):eaag3358. doi: 10.1126/sciimmunol.aag3358. Epub 2017 Apr 14. Sci Immunol. 2017. PMID: 28649674 Free PMC article.

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