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Review
. 2020 Mar 16;15(6):651-672.
doi: 10.1002/asia.201901744. Epub 2020 Feb 18.

N-Centered Radical Directed Remote C-H Bond Functionalization via Hydrogen Atom Transfer

Gautam Kumar  1 , Suman Pradhan  1 , Indranil Chatterjee  1
Affiliations
Review

N-Centered Radical Directed Remote C-H Bond Functionalization via Hydrogen Atom Transfer

Gautam Kumar et al. Chem Asian J. .

Abstract

The N-centered radical directed remote C-H bond functionalization via hydrogen-atom-transfer at distant sites has developed as an enormous potential tool for the organic synthetic chemists. Unactivated and remote secondary and tertiary, as well as selected primary C-H bonds, can be utilized for functionalization by following these methodologies. The synthesis of the heterocyclic scaffolds provides them extra attention for the modern days' developments in this field of unactivated remote C-H bonds functionalizations.

Keywords: C−N/C−C bond formation; N-centered radical; heterocycles; hydrogen atom transfer; remote functionalization.

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