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. 2020 Jan 22;8(1):e16487.
doi: 10.2196/16487.

Feasibility and Accuracy of a Computer-Assisted Self-Interviewing Instrument to Ascertain Prior Immunization With Human Papillomavirus Vaccine by Self-Report: Cross-Sectional Analysis

Carlos R Oliveira  1 , Lital Avni-Singer  1 , Geovanna Badaro  1 , Erin L Sullivan  2 , Sangini S Sheth  3 , Eugene D Shapiro  1 , Linda M Niccolai  2
Affiliations

Feasibility and Accuracy of a Computer-Assisted Self-Interviewing Instrument to Ascertain Prior Immunization With Human Papillomavirus Vaccine by Self-Report: Cross-Sectional Analysis

Carlos R Oliveira et al. JMIR Med Inform. .

Abstract

Background: Ascertaining history of prior immunization with human papillomavirus (HPV) vaccine can be challenging and resource-intensive. Computer-assisted self-interviewing instruments have the potential to address some of the challenges of self-reporting, and may also reduce the time, costs, and efforts associated with ascertaining immunization status.

Objective: This study assesses both the feasibility and the accuracy of a computer-assisted self-interviewing instrument to ascertain a patient's history of immunization with the HPV vaccine.

Methods: We developed both a survey and a Web-based data collection system using computer-assisted self-interviewing to ascertain self-reported HPV vaccine immunization history. We implemented the instrument in a sample of adult women enrolled in an ongoing study of the HPV vaccine. Vaccine records from prior sources of care were reviewed to verify reported immunization history.

Results: Among the 312 participants who provided HPV vaccine immunization history by self-report, almost all (99%) were able to do so using the computer-assisted self-interviewing instrument. The median survey completion time was 10 minutes (IQR 7-17). The accuracy of self-report was 84%, sensitivity was 89%, specificity was 80%, and the negative predictive value was 92%.

Conclusions: We found that it is feasible to collect a history of immunization with the HPV vaccine using a computer-assisted self-interviewing instrument. This approach is likely to be acceptable to adult women and is reasonably accurate in a clinical research setting.

Keywords: accuracy; computer-assisted self-interviewing; human papillomavirus vaccine; self-report.

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Conflict of interest statement

Conflicts of Interest: LMN and SSS have served as Scientific Advisors for Merck. SSS receives Gardasil 9 from Merck at no cost for research.

Figures

Figure 1
Figure 1
Representative screenshot of the app.
Figure 2
Figure 2
Enrollment flowsheet for CASI data collection instrument analyses. CASI: computer-assisted self-interviewing.
See this image and copyright information in PMC

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