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. 2019 Jan-Mar;10(1):31-35.
doi: 10.4103/ccd.ccd_124_18.

Lesion Sterilization and Tissue Repair in Nonvital Primary Teeth: An In vivo Study

Ponnudurai Arangannal  1 , Gomagal Muthiah  1 , J Jeevarathan  1 , P Sankar  1
Affiliations

Lesion Sterilization and Tissue Repair in Nonvital Primary Teeth: An In vivo Study

Ponnudurai Arangannal et al. Contemp Clin Dent. 2019 Jan-Mar.

Abstract

Aim and objective: The aim of this study is to evaluate the clinical and radiographic success of endodontic treatment of nonvital primary teeth using lesion sterilization and tissue repair (LSTR) therapy.

Materials and methods: A sample size of 40 primary molars from 34 children of 3-10 years of age were selected for the study. Nonvital primary molars were treated using LSTR technique with a combination of antibacterial drugs comprising ciprofloxacin, metronidazole, and doxycycline with propylene glycol as vehicle. The procedure was completed in a single appointment. Only analgesics were prescribed postoperatively. Postoperative evaluation was done after 1, 3, 6, and 12 months.

Results: Clinical signs and symptoms got resolved in the 1st-month follow-up itself and continued in the subsequent visits. Radiographic evaluation showed a gradual improvement in success rates through the 12-month follow-up period.

Conclusion: LSTR technique can be considered as an alternative treatment option for nonvital primary teeth avoiding a course of systemic antibiotics to the children. Doxycycline can be used in the drug combination instead of minocycline which also gives higher clinical and radiographic success.

Keywords: Antibiotics; endodontic treatment; lesion sterilization and tissue repair; nonvital primary teeth.

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Conflict of interest statement

There are no conflicts of interest.

Figures

Figure 1
Figure 1
Schematic representation of tooth being treated with lesion sterilization and tissue repair therapy: (1) IRM cement, (2) 3Mix Paste, (3) stainless steel crown
Figure 2
Figure 2
Clinical evaluation: (a) Preoperative clinical picture (b) postoperative clinical picture (12 months)
Figure 3
Figure 3
Radiographic evaluation: (A) Preoperative radiograph (B) postoperative radiograph (12 months) (a) Regeneration. (b) Static. (c) Increase in radiolucency
See this image and copyright information in PMC

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