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. 2020 Jan 29:48:3.
doi: 10.1186/s41182-020-0192-3. eCollection 2020.

Molecular epidemiology of malaria parasite amongst patients in a displaced people's camp in Sudan

Hamza Adam Eshag  1 , Elfadel Elnzer  1 , Elkhatieb Nahied  1 , Mustafa Talib  1 , Ali Mussa  1 , Abd Elhafiz M A Muhajir  1 , Ibrahim Khider Ibrahim  2 , Abdulwali Sabo  3 , Salah-Eldin Gumma Elzaki  4 , Zeehaida Mohamed  5 , Khalid Hajissa  1   5
Affiliations

Molecular epidemiology of malaria parasite amongst patients in a displaced people's camp in Sudan

Hamza Adam Eshag et al. Trop Med Health. .

Abstract

Background: Despite the importance of epidemiological studies in the development of effective control strategies and provision of basic health services for refugees and internally displaced persons (IDPs), data on the prevalence of malaria are limited. Thus, this study was conducted to estimate the molecular prevalence of malaria amongst the displaced population in Ardamata IDP camp in Al-Geneina City, Sudan.

Methods: A cross-sectional study was conducted from July 2018 to December 2018 to estimate malaria prevalence amongst the displaced population in Ardamata IDP camp in Al-Geneina City, Sudan. A total of 380 patients with suspected malaria were recruited. Nested polymerase chain reaction (nPCR) assays were performed to detect the Plasmodium genus and species.

Results: Of 380 patients, 232 (61.1%) were positive for malaria. Plasmodium falciparum was the only prevalent species detected amongst the study population. nPCR analysis revealed that none of the samples had Plasmodium vivax, Plasmodium ovale or Plasmodium malariae. The malaria prevalence rate was higher amongst males (67.1%) than in females (56.8%), and gender was the only risk factor that was significantly associated with malaria infection (p = .042).

Conclusions: Despite control programmes, malaria remains a significant cause of illness amongst a displaced population. The high prevalence of malaria infection in this study indicates that additional health facilities and control strategies should be implemented in displaced camps and the surrounding areas.

Keywords: Displaced camp; Malaria; Molecular epidemiology; Nested PCR; Plasmodium; Sudan.

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Conflict of interest statement

Competing interestsThe authors declare that they have no competing interests.

Figures

Fig. 1
Fig. 1
DNA amplification of Plasmodium species by nPCR. Lane M: 100 bp DNA Marker. Lane NC: negative control. Lane PC: positive control. Lane 1–5: positive samples for P. falciparum t. Lane 6–8: negative control
See this image and copyright information in PMC

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