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Editorial
. 2019 Dec;7(Suppl 8):S275.
doi: 10.21037/atm.2019.11.138.

Can immune biomarkers predict benefit from targeted agents in metastatic renal cell carcinoma?

Renate Pichler  1 , Manuela Schmidinger  2
Affiliations
Editorial

Can immune biomarkers predict benefit from targeted agents in metastatic renal cell carcinoma?

Renate Pichler et al. Ann Transl Med. 2019 Dec.
No abstract available

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Conflict of interest statement

Conflicts of Interest: R Pichler: Honoraria for lectures and advisory boards: Pfizer, BMS, Roche, Ipsen, MSD, Merck, EISAI. Travel grants: BMS, Pfizer, Roche, Pierre Fabre. Research grants: Astellas, Agea Pharma. M Schmidinger: Honoraria for lectures and advisory boards: Pfizer, BMS, Novartis, Roche, Ipsen, Exelixis, EISAI, EUSA, Stellas. Research Grants: Roche, Pfizer. Travel grants: Roche, Ipsen, Pfizer.

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References

    1. Flaifel A, Xie W, Braun DA, et al. PD-L1 Expression and Clinical Outcomes to Cabozantinib, Everolimus, and Sunitinib in Patients with Metastatic Renal Cell Carcinoma: Analysis of the Randomized Clinical Trials METEOR and CABOSUN. Clin Cancer Res 2019;25:6080-8. 10.1158/1078-0432.CCR-19-1135 - DOI - PMC - PubMed
    1. Choueiri TK, Escudier B, Powles T, et al. Cabozantinib versus everolimus in advanced renal cell carcinoma (METEOR): final results from a randomised, open-label, phase 3 trial. Lancet Oncol 2016;17:917-27. 10.1016/S1470-2045(16)30107-3 - DOI - PubMed
    1. Choueiri TK, Halabi S, Sanford BL, et al. Cabozantinib Versus Sunitinib As Initial Targeted Therapy for Patients With Metastatic Renal Cell Carcinoma of Poor or Intermediate Risk: The Alliance A031203 CABOSUN Trial. J Clin Oncol 2017;35:591-7. 10.1200/JCO.2016.70.7398 - DOI - PMC - PubMed
    1. Lalani AA, McGregor BA, Albiges L, et al. Systemic Treatment of Metastatic Clear Cell Renal Cell Carcinoma in 2018: Current Paradigms, Use of Immunotherapy, and Future Directions. Eur Urol 2019;75:100-10. 10.1016/j.eururo.2018.10.010 - DOI - PubMed
    1. Motzer RJ, Tannir NM, McDermott DF, et al. Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma. N Engl J Med 2018;378:1277-90. 10.1056/NEJMoa1712126 - DOI - PMC - PubMed