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Editorial
. 2019 Dec;7(Suppl 8):S309.
doi: 10.21037/atm.2019.10.27.

Gut microbiome, antibiotic use, and immunotherapy responsiveness in cancer

Affiliations
Editorial

Gut microbiome, antibiotic use, and immunotherapy responsiveness in cancer

Jarred P Reed et al. Ann Transl Med. 2019 Dec.
No abstract available

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Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

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References

    1. Matson V, Fessler J, Bao R, et al. The commensal microbiome is associated with anti-PD-1 efficacy in metastatic melanoma patients. Science 2018;359:104-8. 10.1126/science.aao3290 - DOI - PMC - PubMed
    1. Geva-Zatorsky N, Sefik E, Kua L, et al. Mining the Human Gut Microbiota for Immunomodulatory Organisms. Cell 2017;168:928-43.e11. 10.1016/j.cell.2017.01.022 - DOI - PMC - PubMed
    1. Ahmed J, Kumar A, Parikh K, et al. Use of broad-spectrum antibiotics impacts outcome in patients treated with immune checkpoint inhibitors. Oncoimmunology 2018;7:e1507670. 10.1080/2162402X.2018.1507670 - DOI - PMC - PubMed
    1. Derosa L, Routy B, Kroemer G, et al. The intestinal microbiota determines the clinical efficacy of immune checkpoint blockers targeting PD-1/PD-L1. Oncoimmunology 2018;7:e1434468. 10.1080/2162402X.2018.1434468 - DOI - PMC - PubMed
    1. Sen S, Carmagnani Pestana R, Hess K, et al. Impact of antibiotic use on survival in patients with advanced cancers treated on immune checkpoint inhibitor phase I clinical trials. Ann Oncol 2018;29:2396-8. 10.1093/annonc/mdy453 - DOI - PMC - PubMed