Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2019 Dec;7(Suppl 8):S322.
doi: 10.21037/atm.2019.09.155.

Gene-environment interactions determine risk for dementia: the influence of lifestyle on genetic risk for dementia

Kelley T Patten  1 , Pamela J Lein  1
Affiliations
Editorial

Gene-environment interactions determine risk for dementia: the influence of lifestyle on genetic risk for dementia

Kelley T Patten et al. Ann Transl Med. 2019 Dec.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Comment on

References

    1. Kunkle BW, Grenier-Boley B, Sims R, et al. Genetic meta-analysis of diagnosed Alzheimer's disease identifies new risk loci and implicates Abeta, tau, immunity and lipid processing. Nat Genet 2019;51:414-30. 10.1038/s41588-019-0358-2 - DOI - PMC - PubMed
    1. Lambert JC, Ibrahim-Verbaas CA, Harold D, et al. Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease. Nat Genet 2013;45:1452-8. 10.1038/ng.2802 - DOI - PMC - PubMed
    1. Lourida I, Hannon E, Littlejohns TJ, et al. Association of Lifestyle and Genetic Risk With Incidence of Dementia. JAMA 2019. [Epub ahead of print]. 10.1001/jama.2019.9879 - DOI - PMC - PubMed
    1. Lin AL, Zhang W, Gao X, et al. Caloric restriction increases ketone bodies metabolism and preserves blood flow in aging brain. Neurobiol Aging 2015;36:2296-303. 10.1016/j.neurobiolaging.2015.03.012 - DOI - PMC - PubMed
    1. Taylor MK, Swerdlow RH, Sullivan DK. Dietary Neuroketotherapeutics for Alzheimer's Disease: An Evidence Update and the Potential Role for Diet Quality. Nutrients 2019. doi: .10.3390/nu11081910 - DOI - PMC - PubMed