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Editorial
. 2019 Dec;7(Suppl 8):S334.
doi: 10.21037/atm.2019.09.118.

Prolyl hydroxylase domain inhibitors: a new era in the management of renal anemia

Yu Kurata  1 , Tetsuhiro Tanaka  1 , Masaomi Nangaku  1
Affiliations
Editorial

Prolyl hydroxylase domain inhibitors: a new era in the management of renal anemia

Yu Kurata et al. Ann Transl Med. 2019 Dec.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Conflicts of Interest: M Nangaku has received honoraria, advisory fees, or research funding from Kyowa-Kirin, Akebia, Astellas, Chugai, GSK, JT, Taisho-Toyama, Torii, Mitsubishi-Tanabe, Daiichi-Sankyo, Bayer, and Boehringer Ingelheim. T Tanaka has received research grant from JT. The other author has no conflicts of interest to declare.

Comment on

  • Roxadustat for Anemia in Patients with Kidney Disease Not Receiving Dialysis.
    Chen N, Hao C, Peng X, Lin H, Yin A, Hao L, Tao Y, Liang X, Liu Z, Xing C, Chen J, Luo L, Zuo L, Liao Y, Liu BC, Leong R, Wang C, Liu C, Neff T, Szczech L, Yu KP. Chen N, et al. N Engl J Med. 2019 Sep 12;381(11):1001-1010. doi: 10.1056/NEJMoa1813599. Epub 2019 Jul 24. N Engl J Med. 2019. PMID: 31340089 Clinical Trial.

References

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    1. Saito H, Tanaka T, Sugahara M, et al. Inhibition of prolyl hydroxylase domain (PHD) by JTZ-951 reduces obesity-related diseases in the liver, white adipose tissue, and kidney in mice with a high-fat diet. Lab Invest 2019;99:1217-32. 10.1038/s41374-019-0239-4 - DOI - PubMed
    1. Chen N, Hao C, Liu B-C, et al. Roxadustat Treatment for Anemia in Patients Undergoing Long-Term Dialysis. N Engl J Med 2019;381:1011-22. 10.1056/NEJMoa1901713 - DOI - PubMed
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