Standard of usual care defines effectiveness of early goal directed therapy

Vikram Mukherjee¹, Jan Bakker^{1

2

3

4}

Affiliations

¹ Department of Pulmonology and Critical Care, NYU Langone Health, NYU School of Medicine, New York, NY, USA.
² Department of Intensive Care Adults, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
³ Department of Pulmonology and Critical Care, Columbia University Medical Center, New York, NY, USA.
⁴ Department of Intensive Care, Pontificia Universidad Catolica de Chile, Santiago, Chile.

Editorial

Vikram Mukherjee et al. Ann Transl Med. 2019 Dec.

. 2019 Dec;7(Suppl 8):S352.

doi: 10.21037/atm.2019.09.71.

Vikram Mukherjee¹, Jan Bakker^{1

2

3

4}

¹ Department of Pulmonology and Critical Care, NYU Langone Health, NYU School of Medicine, New York, NY, USA.
² Department of Intensive Care Adults, Erasmus MC University Medical Center, Rotterdam, The Netherlands.
³ Department of Pulmonology and Critical Care, Columbia University Medical Center, New York, NY, USA.
⁴ Department of Intensive Care, Pontificia Universidad Catolica de Chile, Santiago, Chile.

No abstract available

Conflict of interest statement

Conflicts of Interest: The authors have no conflicts of interest to declare.

Early goal-directed and lactate-guided therapy in adult patients with severe sepsis and septic shock: a meta-analysis of randomized controlled trials.
Ding XF, Yang ZY, Xu ZT, Li LF, Yuan B, Guo LN, Wang LX, Zhu X, Sun TW. Ding XF, et al. J Transl Med. 2018 Nov 29;16(1):331. doi: 10.1186/s12967-018-1700-7. J Transl Med. 2018. PMID: 30486885 Free PMC article.

1. Adhikari NK, Fowler RA, Bhagwanjee S, et al. Critical care and the global burden of critical illness in adults. Lancet 2010;376:1339-46. 10.1016/S0140-6736(10)60446-1 - DOI - PMC - PubMed
1. Sakr Y, Jaschinski U, Wittebole X, et al. Sepsis in Intensive Care Unit Patients: Worldwide Data From the Intensive Care over Nations Audit. Open Forum Infect Dis 2018;5:ofy313. - PMC - PubMed
1. Rivers E, Nguyen B, Havstad S, et al. Early goal-directed therapy in the treatment of severe sepsis and septic shock. N Engl J Med 2001;345:1368-77. 10.1056/NEJMoa010307 - DOI - PubMed
1. Ding XF, Yang ZY, Xu ZT, et al. Early goal-directed and lactate-guided therapy in adult patients with severe sepsis and septic shock: a meta-analysis of randomized controlled trials. J Transl Med 2018;16:331. 10.1186/s12967-018-1700-7 - DOI - PMC - PubMed
1. ARISE Investigators, ANZICS Clinical Trials Group , Peake SL, et al. Goal-directed resuscitation for patients with early septic shock. N Engl J Med 2014;371:1496-506. 10.1056/NEJMoa1404380 - DOI - PubMed