Circulating tumor cell-based or tissue biopsy-based AR-V7 detection: which provides the greatest clinical utility?
- PMID: 32016072
- PMCID: PMC6976453
- DOI: 10.21037/atm.2019.09.92
Circulating tumor cell-based or tissue biopsy-based AR-V7 detection: which provides the greatest clinical utility?
Conflict of interest statement
Conflicts of Interest: A Rao has served as a paid consultant for QED Therapeutics; has received research funding from Eli Lilly, Sanofi, Genentech, and Clovis Oncology. ES Antonarakis has served as a paid consultant/advisor for Janssen, Astellas, Sanofi and Merck; has received research funding to his institution from Janssen, Johnson & Johnson, Sanofi, Dendreon, Bristol Myers Squibb, Genentech, Novartis and Bayer; and is a co-inventor of a biomarker technology that has been licensed to Qiagen.
Comment on
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Clinical Utility of Circulating Tumour Cell Androgen Receptor Splice Variant-7 Status in Metastatic Castration-resistant Prostate Cancer.Eur Urol. 2019 Nov;76(5):676-685. doi: 10.1016/j.eururo.2019.04.006. Epub 2019 Apr 27. Eur Urol. 2019. PMID: 31036442
References
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- Rao A, Vapiwala N, Ryan CJ, et al. Oligometastatic Prostate Cancer: A Shrinking Subset or an Opportunity for Cure? In: American Society of Clinical Oncology Educational Book, 2019:309-20. Available online: https://ascopubs.org/doi/full/10.1200/EDBK_239041 10.1200/EDBK_239041 - DOI - PubMed
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- Ryan CJ, Smith MR, Fizazi K, et al. Abiraterone acetate plus prednisone versus placebo plus prednisone in chemotherapy-naive men with metastatic castration-resistant prostate cancer (COU-AA-302): final overall survival analysis of a randomised, double-blind, placebo-controlled phase 3 study. Lancet Oncol 2015;16:152-60. 10.1016/S1470-2045(14)71205-7 - DOI - PubMed
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