A TITAN step forward: apalutamide for metastatic castration-sensitive prostate cancer
- PMID: 32016082
- PMCID: PMC6976495
- DOI: 10.21037/atm.2019.09.21
A TITAN step forward: apalutamide for metastatic castration-sensitive prostate cancer
Conflict of interest statement
Conflicts of Interest: T Friedlander participated in an advisory board for Janssen. The other author has no conflicts of interest to declare.
Comment on
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Apalutamide for Metastatic, Castration-Sensitive Prostate Cancer.N Engl J Med. 2019 Jul 4;381(1):13-24. doi: 10.1056/NEJMoa1903307. Epub 2019 May 31. N Engl J Med. 2019. PMID: 31150574 Clinical Trial.
References
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- James ND, Sydes MR, Clarke NW, et al. Addition of docetaxel, zoledronic acid, or both to first-line long-term hormone therapy in prostate cancer (STAMPEDE): survival results from an adaptive, multiarm, multistage, platform randomised controlled trial. Lancet 2016;387:1163-77. 10.1016/S0140-6736(15)01037-5 - DOI - PMC - PubMed
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- Smith MR, Antonarakis ES, Ryan CJ, et al. Phase 2 Study of the Safety and Antitumor Activity of Apalutamide (ARN-509), a Potent Androgen Receptor Antagonist, in the High-risk Nonmetastatic Castration-resistant Prostate Cancer Cohort. Eur Urol 2016;70:963-70. 10.1016/j.eururo.2016.04.023 - DOI - PMC - PubMed
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