Nivolumab without brain radiotherapy is insufficient for the treatment of most patients with brain metastases from clear cell renal cell carcinoma
- PMID: 32016084
- PMCID: PMC6976425
- DOI: 10.21037/atm.2019.09.10
Nivolumab without brain radiotherapy is insufficient for the treatment of most patients with brain metastases from clear cell renal cell carcinoma
Conflict of interest statement
Conflicts of Interest: MT Milano: royalties from Wolters Kluwer (UpToDate); the other authors have no conflicts of interest to declare.
Comment on
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Safety and Efficacy of Nivolumab in Brain Metastases From Renal Cell Carcinoma: Results of the GETUG-AFU 26 NIVOREN Multicenter Phase II Study.J Clin Oncol. 2019 Aug 10;37(23):2008-2016. doi: 10.1200/JCO.18.02218. Epub 2019 Jun 13. J Clin Oncol. 2019. PMID: 31194611 Clinical Trial.
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- George SL, Wang X, Pang H. Cancer Clinical Trials: Current and Controversial Issues in Design and Analysis. CRC Press, 2016.
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- Brastianos PK, Carter SL, Santagata S, et al. Genomic Characterization of Brain Metastases Reveals Branched Evolution and Potential Therapeutic Targets. Cancer Discov 2015;5:1164-77. 10.1158/2159-8290.CD-15-0369 - DOI - PMC - PubMed
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