Notch signaling is essential in collecting duct epithelial cell fate determination during development and maintenance of cell type homeostasis in adult

Ming-Zhi Zhang^{1

2}

Affiliations

¹ Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
² The Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

Editorial

Ming-Zhi Zhang. Ann Transl Med. 2019 Dec.

. 2019 Dec;7(Suppl 8):S376.

doi: 10.21037/atm.2019.12.121.

Ming-Zhi Zhang^{1

2}

¹ Division of Nephrology and Hypertension, Department of Medicine, Vanderbilt University School of Medicine, Nashville, TN, USA.
² The Helen Diller Family Comprehensive Cancer Center, University of California San Francisco, San Francisco, CA, USA.

No abstract available

Conflict of interest statement

Conflicts of Interest: The author has no conflicts of interest to declare.

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1. Seely JC. A brief review of kidney development, maturation, developmental abnormalities, and drug toxicity: juvenile animal relevancy. J Toxicol Pathol 2017;30:125-33. 10.1293/tox.2017-0006 - DOI - PMC - PubMed
1. Mathew S, Chen X, Pozzi A, et al. Integrins in renal development. Pediatr Nephrol 2012;27:891-900. 10.1007/s00467-011-1890-1 - DOI - PubMed
1. Zoetis T, Hurtt ME. Species comparison of anatomical and functional renal development. Birth Defects Res B Dev Reprod Toxicol 2003;68:111-20. 10.1002/bdrb.10013 - DOI - PubMed
1. Márquez MG, Cabrera I, Serrano DJ, et al. Cell proliferation and morphometric changes in the rat kidney during postnatal development. Anat Embryol (Berl) 2002;205:431-40. 10.1007/s00429-002-0262-9 - DOI - PubMed
1. Roy A, Al-bataineh MM, Pastor-Soler NM. Collecting duct intercalated cell function and regulation. Clin J Am Soc Nephrol 2015;10:305-24. 10.2215/CJN.08880914 - DOI - PMC - PubMed