Vitamin D in pediatric health and disease
- PMID: 32017212
- DOI: 10.1111/pai.13154
Vitamin D in pediatric health and disease
Abstract
Several scientific societies established that vitamin D (VD), in its metabolized form 25(OH)D, levels higher than 20 ng/mL are sufficient to ensure optimal bone health, while 25(OH)D levels higher than 30 ng/mL are needed to favor VD extraskeletal actions. However, it has been estimated that approximately 30% of children and 60% of adults worldwide are VD deficient and insufficient, respectively. This is the reason why it is important to provide a practical approach to VD supplementation for infants, children, and adolescents. It is the pediatrician's role to evaluate the modifiable lifestyle risk factors for deficiency, particularly a reduced sun exposure, following an evidence-based approach, and to suggest VD supplementation only when there is a rational reason to support its use.
Keywords: childhood disorders; health; vitamin D3.
© 2020 EAACI and John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
References
REFERENCES
-
- Holick MF. Vitamin D deficiency. New Engl J Med. 2007;357:266-281.
-
- Uday S, Wolfgang H. Prevention of rickets and osteomalacia in the UK: political action overdue. Arch Dis Child. 2018;103:901-906.
-
- Boot AM, de Ridder MA, van der Sluis IM, et al. Peak bone mineral density, lean body mass, and fractures. Bone. 2010;46:336-341.
-
- Vierucci F, Saggese G, Cimaz R. Osteoporosis in childhood. Current opinion in rheumatology. 2017;29(5):535-546.
-
- Muehleisen B, Gallo RL. Vitamin D in allergic disease: shedding light on a complex problem. J Allerg Clin Immunol. 2013;131:324-329.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Medical
