Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2020 Sep;98(6):e743-e746.
doi: 10.1111/aos.14368. Epub 2020 Feb 3.

Pseudophakic negative dysphotopsia and intraocular lens orientation: a prospective double-masked randomized controlled trial

Gemma S L Manasseh  1 , Edward W J Pritchard  1 , Alice E J Rothwell  1 , Jonathan Luck  1
Affiliations
Free article
Randomized Controlled Trial

Pseudophakic negative dysphotopsia and intraocular lens orientation: a prospective double-masked randomized controlled trial

Gemma S L Manasseh et al. Acta Ophthalmol. 2020 Sep.
Free article

Abstract

Purpose: To determine whether horizontal orientation of the intraocular lens optic-haptic junctions has an effect on the incidence of pseudophakic negative dysphotopsia.

Methods: Single-centre prospective double-masked randomized controlled trial. 220 eyes of 201 participants undergoing routine cataract surgery were randomized to receive their intraocular lens either orientated with the optic-haptic junctions at 180° ('horizontal') or without manipulation following implantation (control). Patients were excluded according to age (<19 and > 99 years), coexisting eye disease affecting visual function and insufficient cognitive function to complete the study. In the fourth postoperative week, a telephone interview was conducted to determine rates of negative dysphotopsia. The data were analysed to provide the relative risk of negative dysphotopsia with horizontal orientation of the intraocular lens (IOL) optic-haptic junctions compared with standard treatment.

Results: Orientating the IOL optic-haptic junctions horizontally halved the incidence of pseudophakic negative dysphotopsia in the fourth postoperative week (9/110 in the intervention group; 18/110 in the control group; RR: 0.50, 95% confidence interval: 0.235-1.064, p = 0.072). The overall incidence of negative dysphotopsia was 12.2% (27/220 participating eyes). No intraoperative adverse effects of intraocular lens rotation were reported.

Conclusion: The simple intraoperative manoeuvre of rotating the intraocular lens to orientate the optic-haptic junctions at 180° may be a safe and effective measure to reduce the risk of developing postoperative pseudophakic negative dysphotopsia in the first postoperative month. This is the first report that demonstrates the benefit of horizontal optic-haptic junction positioning to be sustained beyond the first postoperative day.

Keywords: dysphotopsia; haptic; intraocular lens; negative; orientation; pseudophakic.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

References

    1. Altman DG (1991): Practical statistics for medical research. London: Chapman and Hall.
    1. Bournas P, Drazinos S, Kanellas D, Arvanitis M & Vaikoussis E (2007): Dysphotopsia after cataract surgery: comparison of four different intraocular lenses. Ophthalmologica 221: 378-383.
    1. Burke TR & Benjamin L (2014): Sulcus-fixated intraocular lens implantation for the management of negative dysphotopsia. J Cataract Refract Surg 40: 1469-1472.
    1. Cooke DL (2010): Negative dysphotopsia after temporal corneal incisions. J Cataract Refract Surg 36: 671-672.
    1. Davison JA (2000): Positive and negative dysphotopsia in patients with acrylic intraocular lenses. J Cataract Refract Surg 26: 1346-1355.

Publication types

LinkOut - more resources