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Review
. 2020 Apr 1:1732:146653.
doi: 10.1016/j.brainres.2020.146653. Epub 2020 Feb 1.

Ethical issues related to brain organoid research

Insoo Hyun  1 , J C Scharf-Deering  2 , Jeantine E Lunshof  3
Affiliations
Review

Ethical issues related to brain organoid research

Insoo Hyun et al. Brain Res. .

Abstract

This review provides a snapshot of the current ethical issues related to research with human brain organoids. The issues fall into the following main themes: research oversight; human biomaterials procurement and donor consent; translational delivery; animal research; and organoid consciousness and moral status. Each of these areas poses challenges for researchers, bioethicists, regulators, research institutions, and tissue banks. However, progress can be made if these parties build on past experiences with stem cell research, ethics, and policy, but adapted accordingly to new aspects of brain organoid research.

Keywords: Animal research; Brain organoids; Consciousness; Consent; Ethics; Research oversight.

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References

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