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Review
. 2020 Jan 31;53(2):e9560.
doi: 10.1590/1414-431X20199560. eCollection 2020.

The contribution of Latin American research to HPV epidemiology and natural history knowledge

Affiliations
Review

The contribution of Latin American research to HPV epidemiology and natural history knowledge

L Sichero et al. Braz J Med Biol Res. .

Abstract

Our aim was to review the major contributions of studies conducted in different Latin American (LA) countries to the field of human papillomavirus (HPV) epidemiology, natural history, risk of disease, and prevention strategies, mainly in the uterine cervix. Although cytological screening is established in several countries in LA, incidence and mortality rates from cervical cancer (CC) are still extremely high. Finally, data from large cohort studies conducted in LA countries provided seminal data to propose primary and secondary prevention modalities: the HPV vaccine has been introduced in the national immunization programs of several LA countries and multiple screening experiences using HPV testing are under evaluation in the region.

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References

    1. Bouvard V, Baan R, Straif K, Grosse Y, Secretan B, El Ghissassi F, et al. A review of human carcinogens-part B: biological agents. Lancet Oncol. 2009;10:321–322. doi: 10.1016/S1470-2045(09)70096-8. - DOI - PubMed
    1. Bzhalava D, Eklund C, Dillner J. International standardization and classification of human papillomavirus types. Virology. 2015;476:341–344. doi: 10.1016/j.virol.2014.12.028. - DOI - PubMed
    1. Sichero L, Villa LL. Epidemiological and functional implications of molecular variants of human papillomavirus. Braz J Med Biol Res. 2006;39:707–717. doi: 10.1590/S0100-879X2006000600002. - DOI - PubMed
    1. Mirabello L, Yeager M, Cullen M, Boland JF, Chen Z, Wentzensen N, et al. HPV16 Sublineage associations with histology-specific cancer risk using HPV whole-genome sequences in 3200 women. J Natl Cancer Inst. 2016;108:djw100. doi: 10.1093/jnci/djw100. pii. - DOI - PMC - PubMed
    1. Burk RD, Harari A, Chen Z. Human papillomavirus genome variants. Virology. 2013;445:232–243. doi: 10.1016/j.virol.2013.07.018. - DOI - PMC - PubMed

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