Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 May;14(3):340-348.
doi: 10.1111/irv.12719. Epub 2020 Feb 5.

Characteristics of hospitalizations with an influenza diagnosis, France, 2012-2013 to 2016-2017 influenza seasons

Mathilde Pivette  1 , Nathalie Nicolay  1 , Virginie de Lauzun  1 , Bruno Hubert  1
Affiliations

Characteristics of hospitalizations with an influenza diagnosis, France, 2012-2013 to 2016-2017 influenza seasons

Mathilde Pivette et al. Influenza Other Respir Viruses. 2020 May.

Abstract

Background: Estimating the global burden of influenza hospitalizations is required to allocate resources and assess interventions that aim to prevent severe influenza. In France, the current routine influenza surveillance system does not fully measure the burden of severe influenza cases. The objective was to describe the characteristics and severity of influenza hospitalizations by age-group and by season between 2012 and 2017.

Methods: All hospitalizations with a diagnosis of influenza in metropolitan France between July 2012 and June 2017 were extracted from the French national hospital discharge database (PMSI). For each season, the total number of influenza hospitalizations, admissions to intensive care units (ICU), proportion of deaths, lengths of stay, and distribution in diagnosis-related groups were described by age-group.

Results: Over the five seasons, 91 255 hospitalizations with a diagnosis of influenza were identified. The average influenza hospitalization rate varied from 13/100 000 in 2013-2014 to 46/100 000 in 2016-2017. A high rate was observed in elderlies during the 2014-2015 and 2016-2017 seasons, dominated by A(H3N2) virus. The youngest were impacted in 2015-2016, dominated by B/Victoria virus. The proportion of influenza hospitalizations with ICU admission was 10%, and was higher in age-group 40-79 years. The proportion of deaths and length of stay increased with age.

Conclusions: The description of influenza hospitalizations recorded in the PMSI give key information on the burden of severe influenza in France. Analyses of these data annually is valuable in order to document the severity of influenza hospitalizations by age-group and according to the circulating influenza viruses.

Keywords: France; epidemics; hospitalizations; influenza; intensive care units.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Weekly number of hospitalizations with an influenza diagnosis, 2012‐2017, metropolitan France
Figure 2
Figure 2
Hospitalization rate (/100 000) of influenza per age‐group and per season, 2012‐2017, metropolitan France
Figure 3
Figure 3
Weekly rate of influenza hospitalizations (/100 000) by age‐group and by season, and classification within each age‐group (95th percentile), 2012‐2017, metropolitan France
Figure 4
Figure 4
Total number of days of influenza hospitalizations by age‐group and by season, 2012‐2017, metropolitan France
See this image and copyright information in PMC

References

    1. Pelat C, Bonmarin I, Ruello M, et al. Improving regional influenza surveillance through a combination of automated outbreak detection methods: the 2015/16 season in France. Euro Surveill. 2017;22(32):30593. - PMC - PubMed
    1. Bonmarin I, Belchior E, Bergounioux J, et al. Intensive care unit surveillance of influenza infection in France: the 2009/10 pandemic and the three subsequent seasons. Euro Surveill. 2015;20(46). 10.2807/1560-7917.ES.2015.20.46.30066 - DOI - PubMed
    1. Thompson WW, Shay DK, Weintraub E, et al. Influenza‐associated hospitalizations in the United States. JAMA. 2004;292(11):1333‐1340. - PubMed
    1. Rodrigues E, Machado A, Silva S, Nunes B. Excess pneumonia and influenza hospitalizations associated with influenza epidemics in Portugal from season 1998/1999 to 2014/2015. Influenza Other Respir Viruses. 2018;12(1):153‐160. - PMC - PubMed
    1. Oliva J, Delgado‐Sanz C, Larrauri A. Estimating the burden of seasonal influenza in Spain from surveillance of mild and severe influenza disease, 2010–2016. Influenza Other Respir Viruses. 2018;12(1):161‐170. - PMC - PubMed

MeSH terms