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. 2020 Feb 5;3(2):e1920294.
doi: 10.1001/jamanetworkopen.2019.20294.

Trends in Liver Disease Etiology Among Adults Awaiting Liver Transplantation in the United States, 2014-2019

Affiliations

Trends in Liver Disease Etiology Among Adults Awaiting Liver Transplantation in the United States, 2014-2019

Robert J Wong et al. JAMA Netw Open. .

Abstract

This cohort study provides updated assessments of liver disease etiology trends among adults awaiting liver transplantation in the United States from 2014 to 2019.

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Conflict of interest statement

Conflict of Interest Disclosures: None reported.

Figures

Figure.
Figure.. Liver Disease Etiology Trends Among Adult Liver Transplantation Waiting List Registrants in the United States
Data for 2019 were available from January 1 to March 31, 2019. The total number of wait-listed registrants for 2019 was extrapolated by multiplying the numbers from January 1 to March 31 by 4. AIH indicates autoimmune hepatitis; ALD, alcohol-associated liver disease; HBV, hepatitis B virus; HCC, hepatocellular carcinoma; HCV, hepatitis C virus; NASH, nonalcoholic steatohepatitis; PBC, primary biliary cholangitis; and PSC, primary sclerosing cholangitis.

References

    1. Wong T, Dang K, Ladhani S, Singal AK, Wong RJ. Prevalence of alcoholic fatty liver disease among adults in the United States, 2001-2016. JAMA. 2019;321(17):1723-1725. doi: 10.1001/jama.2019.2276 - DOI - PMC - PubMed
    1. Younossi ZM, Blissett D, Blissett R, et al. The economic and clinical burden of nonalcoholic fatty liver disease in the United States and Europe. Hepatology. 2016;64(5):1577-1586. doi: 10.1002/hep.28785 - DOI - PubMed
    1. Wong RJ, Aguilar M, Cheung R, et al. Nonalcoholic steatohepatitis is the second leading etiology of liver disease among adults awaiting liver transplantation in the United States. Gastroenterology. 2015;148(3):547-555. doi: 10.1053/j.gastro.2014.11.039 - DOI - PubMed
    1. Younossi Z, Stepanova M, Ong JP, et al. ; Global Nonalcoholic Steatohepatitis Council . Nonalcoholic steatohepatitis is the fastest growing cause of hepatocellular carcinoma in liver transplant candidates. Clin Gastroenterol Hepatol. 2019;17(4):748-755.e3. - PubMed
    1. Dang K, Hirode G, Singal AK, Sundaram V, Wong RJ. Alcoholic liver disease epidemiology in the United States: a retrospective analysis of three United States databases. Am J Gastroenterol. 2019. doi: 10.14309/ajg.0000000000000380 - DOI - PubMed