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. 2020 Apr;9(3):292-296.
doi: 10.1002/cpdd.781. Epub 2020 Feb 5.

Lasmiditan: Its Development and Potential Use

Amanda E Macone  1 , Michael D Perloff  1
Affiliations

Lasmiditan: Its Development and Potential Use

Amanda E Macone et al. Clin Pharmacol Drug Dev. 2020 Apr.
No abstract available

Keywords: 5HT1f; cardiovascular; lasmiditan; migraine; triptan.

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References

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    1. Goadsby PJ, Holland PR, Martins-Oliveira M, Hoffmann J, Schankin C, Akerman S. Pathophysiology of migraine: a disorder of sensory processing. Physiol Rev. 2017;97:553-622.
    1. Lanfumey L, Hamon M, 5-HT1 receptors. Curr Drug Targets CNS Neurol Disord. 2004;3(1):1-10.
    1. Adham N, Bard JA, Zgombick JM, et al. Cloning and characterization of the guinea pig 5-HT1F receptor subtype: a comparison of the pharmacological profile to the human species homolog. Neuropharmacology. 1997;36:569-576.
    1. Goldstein DJ, Roon KI, Offen WW, et al. Selective serotonin 1F (5-HT1F) receptor agonist LY334370 for acute migraine: a randomized controlled trial. Lancet. 2001;358:1230-1234.

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