Fused Azolo-Quinoxalines: Candidates for Medicinal Chemistry. A Review of their Biological Applications

Abstract

Heterocyclic compounds hold a huge and recognized place in the field of medicinal chemistry thanks to their multiple biological activities. Their synthetic pathways allow their easy and rapid access due to different bond-forming methodologies and provide a huge amount of multi-functionalized compounds for drug delivery. The syntheses of heterocyclic compounds are today well known for the majority, described and reviewed in an extensive literature. In this review, we choose to gather and classify available information concerning the biological activities of quinoxaline-based compounds annulated at bond a containing one and more nitrogen atoms in the fused azole ring.

Keywords: Azolo-quinoxaline; antibacterial; anticancer; antiobesity; antiparasitic; antiviral; cardiomodulator; immunomodulator; neuromodulator.