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. 2020 Feb 6;14(2):e0007931.
doi: 10.1371/journal.pntd.0007931. eCollection 2020 Feb.

Role of DNA-detection-based tools for monitoring the soil-transmitted helminth treatment response in drug-efficacy trials

Javier Gandasegui  1   2 , María Martínez-Valladares  3   4 , Berta Grau-Pujol  1   2   5 , Alejandro J Krolewiecki  1   6 , Rafael Balaña-Fouce  7 , Woyneshet Gelaye  8 , Lisette van Lieshout  9 , Stella Kepha  10   11   12 , Inácio Mandomando  2   13 , José Muñoz  1 ; Stopping Transmission Of intestinal Parasites (STOP) project consortium
Affiliations

Role of DNA-detection-based tools for monitoring the soil-transmitted helminth treatment response in drug-efficacy trials

Javier Gandasegui et al. PLoS Negl Trop Dis. .
No abstract available

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Conflict of interest statement

The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Putative benzimidazole-resistance SNP in human STHs.
(A) Sequence information displayed in GenBank’s flat file; the boxes represent exons, whereas the lines represent introns. (B) Detailed nucleotide sequence of the three putative resistance SNPs and the amino-acid transcript at codons 167, 198, and 200. Al, Ascaris lumbricoides β-tubulin 1 sequence, partial cds (GenBank: FJ501301); cds, coding sequence; Na, Necator americanus β-tubulin 1 sequence, complete cds (GenBank: EF392851); STH, soil-transmitted helminth; Tt, Trichuris truchiura β-tubulin 1 sequence, complete cds (GenBank: AF034219).
See this image and copyright information in PMC

References

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