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. 2020 Feb 5;105(3):395-397.
doi: 10.1016/j.neuron.2020.01.013.

Photocontrol of Metabotropic Glutamate Receptors: When One Agonist Is Not Enough, Make It Two

Laetitia Mony  1 , Pierre Paoletti  2
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Photocontrol of Metabotropic Glutamate Receptors: When One Agonist Is Not Enough, Make It Two

Laetitia Mony et al. Neuron. .
Free article

Abstract

A current major challenge lies in controlling molecularly defined brain receptor and channel populations to investigate their function in vivo. In this issue of Neuron, Acosta-Ruiz et al. (2020) developed a highly versatile molecular toolkit to efficiently manipulate specific metabotropic glutamate receptor subtypes in brain circuits with light.

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