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. 2020 Jan 22:7:2374289519897383.
doi: 10.1177/2374289519897383. eCollection 2020 Jan-Dec.

Educational Case: Esophageal Carcinoma

Jesse Lee Kresak  1 , Mark Kavesh  1 , Michael Feely  1
Affiliations

Educational Case: Esophageal Carcinoma

Jesse Lee Kresak et al. Acad Pathol. .

Abstract

The following fictional case is intended as a learning tool within the Pathology Competencies for Medical Education (PCME), a set of national standards for teaching pathology. These are divided into three basic competencies: Disease Mechanisms and Processes, Organ System Pathology, and Diagnostic Medicine and Therapeutic Pathology. For additional information, and a full list of learning objectives for all three competencies, see http://journals.sagepub.com/doi/10.1177/2374289517715040.1.

Keywords: Barrett esophagus; environmental influences; esophageal carcinoma; gastrointestinal neoplasia; gastrointestinal tract; neoplasia; organ system pathology; pathology competencies.

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Conflict of interest statement

Declaration of Conflicting Interests: The author(s) declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
Endoscopy shows a fungating mass at the gastroesophageal junction (GEJ) with salmon-colored mucosa proximal to the mass.
Figure 2.
Figure 2.
Biopsy of esophageal mass, hematoxylin and eosin (H&E) stained section, ×200 magnification. Adenocarcinoma characterized by irregular, infiltrating glands.
Figure 3.
Figure 3.
A, Biopsy of salmon-colored mucosa adjacent to gastroesophageal junction, hematoxylin and eosin (H&E) stained section, ×100 magnification. B, Same area, ×400 magnification showing dysplastic features. Black arrows indicate goblet cells. Yellow arrows point to dysplastic features including hyperchromatic, enlarged nuclei, and mitotic figures. The star overlies the squamous epithelium.
Figure 4.
Figure 4.
Biopsy of esophageal squamous cell carcinoma, hematoxylin and eosin (H&E) stained section, ×100 magnification.
See this image and copyright information in PMC

References

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