Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Randomized Controlled Trial
. 2020 Sep;24(9):2490-2508.
doi: 10.1007/s10461-020-02806-4.

A Pilot Test of Game Changers, a Social Network Intervention to Empower People with HIV to be Prevention Advocates in Uganda

Affiliations
Randomized Controlled Trial

A Pilot Test of Game Changers, a Social Network Intervention to Empower People with HIV to be Prevention Advocates in Uganda

Laura M Bogart et al. AIDS Behav. 2020 Sep.

Abstract

We conducted a pilot randomized controlled trial of Game Changers, a 6-session group intervention that empowers people with HIV to be HIV prevention advocates in their social networks. Ninety-nine people with HIV (51 intervention, 48 wait-list control) and 58 of their social network members (alters) completed baseline and 5- and 8-month post-baseline assessments. Results indicated high acceptability, demonstrated by participants' and facilitators' positive attitudes qualitatively and favorable ratings of intervention sessions quantitatively, and high feasibility (76% attended all intervention sessions). Intention-to-treat analyses indicated significantly increased HIV prevention advocacy among HIV-positive participants and alters [b (SE) = 0.4 (0.2), p = .017; b (SE) = 0.4 (0.2), p = .035]; reduced internalized HIV stigma [b (SE) = - 0.3 (0.1), p = .012], increased HIV-serostatus disclosure [b (SE) = 0.1 (0.1), p = .051], and increased social network density among HIV-positive participants [b (SE) = 0.1 (0.03), p = .004]; and marginally reduced condomless sex among alters [OR (95% CI) = 0.3 (0.1-1.2), p = .08]. Positioning people with HIV as central to prevention has the potential to reduce stigma and improve prevention outcomes throughout social networks.

Keywords: HIV/AIDS; Health promotion/prevention; Peer intervention; Social network analysis; Uganda.

PubMed Disclaimer

Conflict of interest statement

Conflict of Interest: The authors declare that they have no conflict of interest.

Figures

Figure I.
Figure I.
Conceptual Model of Game Changers Intervention
Figure II.
Figure II.
CONSORT Flow Diagram for Index Participants (People with HIV)
Figure III.
Figure III.
CONSORT Flow Diagram for Social Network Members (Alters) of Index Participants
Figure IV.
Figure IV.
Social network diagrams for intervention and control participants at baseline and 8-month follow-up, illustrating changes in density over time. Both participants have about average density at baseline. The intervention participant’s density remains similar over time (.3 at baseline, .3 at follow-up), whereas the control participant’s density decreases (.3 at baseline, .2 at follow-up). The size of the nodes correspond to the number of ties for each alter, with the largest node in each diagram representing the maximum degree value.

References

    1. UNAIDS. AIDSinfo. Available from: http://aidsinfo.unaids.org/.
    1. UPHIA. Uganda population-based HIV impact assessment, UPHIA 2016–2017. 2017. Available from: https://afro.who.int/sites/default/files/2017-08/UPHIA%20Uganda%20factsh....
    1. Avert. HIV and AIDS in Uganda. 2019. Available from: https://www.avert.org/professionals/hiv-around-world/sub-saharan-africa/....
    1. Joint United Nations Programme on HIV/AIDS (UNAIDS). Ending AIDS: Progress towards the 90–90-90 targets. 2017. Available from: http://www.unaids.org/sites/default/files/media_asset/Global_AIDS_update....
    1. AVAC. Uganda: A snapshot of PrEP scale-up, registration and resources for Uganda. 2018. Available from: https://www.prepwatch.org/country/uganda/.

Publication types