Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2020 Jul;26(5):948-954.
doi: 10.1111/odi.13303. Epub 2020 Feb 21.

Depression symptoms and recurrent aphthous stomatitis-Evidence from a population-based study in Indonesia

Ninuk Hariyani  1   2 , Taufan Bramantoro  2 , Rahul Nair  1 , Ankur Singh  3   4 , Kaushik Sengupta  5
Affiliations

Depression symptoms and recurrent aphthous stomatitis-Evidence from a population-based study in Indonesia

Ninuk Hariyani et al. Oral Dis. 2020 Jul.

Abstract

Objectives: This study aims to report the prevalence and distribution of recurrent aphthous stomatitis (RAS) among Indonesian adults and to test the relationship between symptom of depression and RAS.

Methods: Data from the 2007 Indonesia Family Life Survey (IFLS 2007) were analysed to assess the association between symptom of depression and RAS. The prevalence of RAS in the previous month was self-reported. Symptom of depression was measured using the 10-item Center for Epidemiologic Studies Depression (CES-D) scale. The distribution of RAS according to age, sex and level of stress was also presented in the bivariate analysis. Multivariable logistic regression models were fitted to test associations between symptom of depression and RAS, controlling for age, sex and the stress level.

Results: The previous month prevalence of RAS in Indonesian population was 12%. The adjusted odds ratios (ORs) from the logistic regression models indicate that, for each unit increase in the CES-D depression score (range: 0-30), there was a 9% increase in the odds of having RAS (OR: 1.09, 95%CI: 1.08-1.10). Being older and being male was related with lower prevalence of RAS.

Conclusions: A higher score of depression was related to a higher prevalence of RAS. This association was persistent even after controlling for age, sex and the level of stress.

Keywords: Indonesia; depression; population-based study; recurrent aphthous stomatitis.

PubMed Disclaimer

References

REFERENCES

    1. Abdullah, M. J. (2013). Prevalence of recurrent aphthous ulceration experience in patients attending Piramird dental speciality in Sulaimani City. Journal of Clinical and Experimental Dentistry, 5(2), 89-94. https://doi.org/10.4317/jced.51042
    1. Akintoye, S. O., & Greenberg, M. S. (2014). Recurrent aphthous stomatitis. Dental Clinics of North America, 58(2), 281-297. https://doi.org/10.1016/j.cden.2013.12.002
    1. Al-Omiri, M. K., Karasneh, J., & Lynch, E. (2012). Psychological profiles in patients with recurrent aphthous ulcers. International Journal of Oral & Maxillofacial Surgery, 41(3), 384-388. https://doi.org/10.1016/j.ijom.2011.12.024
    1. Alshahrani, S., & Baccaglini, L. (2014). Psychological screening test results for stress, depression, and anxiety are variably associated with clinical severity of recurrent aphthous stomatitis and oral lichen planus. The Journal of Evidence-Based Dental Practice, 14(4), 206-208. https://doi.org/10.1016/j.jebdp.2014.10.004
    1. Aminabadi, N. A. (2008). Recurrent aphthous stomatitis may be initiated by traumatic epithelial implantation and sustained by localized pathergic status. Medical Hypotheses, 70(3), 522-524. https://doi.org/10.1016/j.mehy.2007.06.034

LinkOut - more resources