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. 1988 Dec;27(6):462-4.
doi: 10.1093/rheumatology/27.6.462.

Increased urinary excretion of glycosaminoglycans in insulin-dependent diabetic patients with limited joint mobility

G C Priestley  1 , A Collier, D M Matthews, B F Clarke
Affiliations

Increased urinary excretion of glycosaminoglycans in insulin-dependent diabetic patients with limited joint mobility

G C Priestley et al. Br J Rheumatol. 1988 Dec.

Abstract

Urinary excretion of glycosaminoglycans (GAG) was measured in 24-h specimens collected from 27 insulin-dependent male diabetic patients and 22 healthy males of similar ages. Excretion relative to creatinine was increased by 35% in the diabetic group as a whole (p less than 0.02). Twelve patients with limited joint mobility (cheiroarthropathy) formed a subgroup with high excretion (69% above controls), those without limited joint mobility being similar to controls. There was no correlation of retinopathy with GAG excretion.

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