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Comment
. 2020 Feb 6;26(2):131-133.
doi: 10.1016/j.stem.2020.01.003.

Organoids Develop Motor Skills: 3D Human Neuromuscular Junctions

Justin K Ichida  1 , Chien-Ping Ko  2
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Free article
Comment

Organoids Develop Motor Skills: 3D Human Neuromuscular Junctions

Justin K Ichida et al. Cell Stem Cell. .
Free article

Abstract

Stem cell technology enables the production of three-dimensional organ-like structures, but engineering multi-tissue anatomy has proven difficult. In this issue of Cell Stem Cell, Martins et al. (2020) show that generating a common progenitor cell for posterior spinal cord and muscle enables the formation of functional neuromuscular junctions in single organoids.

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Conflict of interest statement

Declaration of Interests C.-P.K. is a Cure SMA Translational Advisory Council member and J.K.I. is a co-founder of AcuraStem, Inc.

Comment on

  • Self-Organizing 3D Human Trunk Neuromuscular Organoids.
    Faustino Martins JM, Fischer C, Urzi A, Vidal R, Kunz S, Ruffault PL, Kabuss L, Hube I, Gazzerro E, Birchmeier C, Spuler S, Sauer S, Gouti M. Faustino Martins JM, et al. Cell Stem Cell. 2020 Feb 6;26(2):172-186.e6. doi: 10.1016/j.stem.2019.12.007. Epub 2020 Jan 16. Cell Stem Cell. 2020. PMID: 31956040

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