Somatic Mutations in Liver Disease: Adaptation Without Carcinogenesis?
- PMID: 32034958
- DOI: 10.1002/hep.31169
Somatic Mutations in Liver Disease: Adaptation Without Carcinogenesis?
Comment on
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Somatic Mutations Increase Hepatic Clonal Fitness and Regeneration in Chronic Liver Disease.Cell. 2019 Apr 18;177(3):608-621.e12. doi: 10.1016/j.cell.2019.03.026. Epub 2019 Apr 4. Cell. 2019. PMID: 30955891 Free PMC article.
References
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- Zhu M, Lu T, Jia Y, Luo X, Gopal P, Li L, et al. Somatic mutations increase hepatic clonal fitness and regeneration in chronic liver disease. Cell 2019;177:608-621.e612.
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- Martincorena I, Fowler JC, Wabik A, Lawson ARJ, Abascal F, Hall MWJ, et al. Somatic mutant clones colonize the human esophagus with age. Science 2018;362:911-917.
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- The Cancer Genome Atlas Research Network. Comprehensive and integrative genomic characterization of hepatocellular carcinoma. Cell 2017;169:1327-1341.e1323.
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- Craig AJ, von Felden J, Garcia-Lezana T, Sarcognato S, Villanueva A. Tumour evolution in hepatocellular carcinoma. Nat Rev Gastroenterol Hepatol 2019 Dec 2. https://doi.org/10.1038/s41575-019-0229-4. [Epub ahead of print]
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