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Randomized Controlled Trial
. 2020 Feb;48(2):300060520902606.
doi: 10.1177/0300060520902606.

Comparative study of the Ambu® AuraOnce™ laryngeal mask and endotracheal intubation in anesthesia airway management during neurosurgery

Qiaoyun Zhang  1 , Yongxing Sun  1 , Baoguo Wang  1 , Shuangyan Wang  1 , Feng Mu  1 , Yunxin Zhang  2
Affiliations
Randomized Controlled Trial

Comparative study of the Ambu® AuraOnce™ laryngeal mask and endotracheal intubation in anesthesia airway management during neurosurgery

Qiaoyun Zhang et al. J Int Med Res. 2020 Feb.

Abstract

Objective: To investigate the feasibility and efficacy of the Ambu® AuraOnce™ laryngeal mask (LMA) compared with endotracheal intubation (ETI) during supratentorial tumor resection in the right lateral decubitus position.

Methods: This was a randomized controlled trial of LMA compared with ETI in patients who were scheduled to undergo supratentorial tumor resection in the right lateral decubitus position. The patients were randomized to the LMA (n = 40) and ETI groups (n = 40). The hemodynamic parameters (primary outcome) and mechanical ventilation parameters, anesthetic dose, and complications as well as quality of anesthesia recovery (secondary outcomes) were compared.

Results: Patients in the LMA group exhibited lower mean arterial pressure (MAP) and heart rate (HR) compared with ETI. Nine and two patients received esmolol during intubation and extubation, respectively. The airway pressure (AP) in the LMA group was higher compared with the ETI group 60 minutes after the start of surgery. Compared with the ETI group, the sufentanil dose was lower by 24% and the anesthesia recovery rate was better in the LMA group.

Conclusions: LMA can improve hemodynamic stability in patients undergoing supratentorial tumor resection in the right lateral decubitus position. If there is a clinical need and no contraindication, LMA could replace ETI.

Keywords: Laryngeal mask; airway management; comparative study; endotracheal intubation; hemodynamic stability; neurosurgical anesthesia; supratentorial tumor resection.

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Figures

Figure 1.
Figure 1.
MAP at different time points in the LMA and ETI groups. *p < 0.05 and **p < 0.01 versus ETI group, respectively. (Main effect: F, p = 6.103, 0.016, time effect: 51.541, <0.001, time-group interaction effect: 3.116, 0.048).
Figure 2.
Figure 2.
HR at different time points in the LMA and ETI groups. **p < 0.01 versus ETI group. (Main effect: F, p = 18.839, <0.001, time effect: 10.699, <0.001, time-group interaction effect: 10.527, <0.001).
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