Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Editorial
. 2020 Feb;359(2):70-72.
doi: 10.1016/j.amjms.2019.11.010. Epub 2019 Nov 29.

TGF-β and Diabetic Nephropathy: Lessons Learned Over the Past 20 Years

Affiliations
Editorial

TGF-β and Diabetic Nephropathy: Lessons Learned Over the Past 20 Years

Leslie S Gewin. Am J Med Sci. 2020 Feb.
No abstract available

PubMed Disclaimer

Comment on

References

    1. Ziyadeh FN, Sharma K, Ericksen M, et al. Stimulation of collagen gene expression and protein synthesis in murine mesangial cells by high glucose is mediated by autocrine activation of transforming growth factor-beta. J Clin Invest. 1994;93:536–542. - PMC - PubMed
    1. Yamamoto T, Nakamura T, Noble NA, et al. Expression of transforming growth factor beta is elevated in human and experimental diabetic nephropathy. Proc Natl Acad Sci USA. 1993;90:1814–1818. - PMC - PubMed
    1. Daniels MC, McClain DA, Crook ED. Transcriptional regulation of transforming growth factor beta1 by glucose: investigation into the role of the hexosamine biosynthesis pathway. Am J Med Sci. 2000;319:138–142. - PubMed
    1. McClain DA, Paterson AJ, Roos MD, et al. Glucose and glucosamine regulate growth factor gene expression in vascular smooth muscle cells. Proc Natl Acad Sci USA. 1992;89:8150–8154. - PMC - PubMed
    1. Yu L, Border WA, Huang Y, et al. TGF-beta isoforms in renal fibrogenesis. Kidney Int. 2003;64:844–856. - PubMed

Publication types

MeSH terms

Substances