Is PD-1 blockade a potential therapy for HBV?
- PMID: 32040093
- PMCID: PMC7001582
- DOI: 10.1016/j.jhepr.2019.07.007
Is PD-1 blockade a potential therapy for HBV?
Comment on
-
HBeAg seroconversion is associated with a more effective PD-L1 blockade during chronic hepatitis B infection.JHEP Rep. 2019 Jun 28;1(3):170-178. doi: 10.1016/j.jhepr.2019.06.001. eCollection 2019 Sep. JHEP Rep. 2019. PMID: 32039367 Free PMC article.
References
-
- Guidotti LG, Chisari FV. Immunobiology and pathogenesis of viral hepatitis. Annu Rev Pathol. 2006;1:23–61. - PubMed
-
- Lan P, Zhang C, Han Q, Zhang J, Tian Z. Therapeutic recovery of hepatitis B virus (HBV)-induced hepatocyte-intrinsic immune defect reverses systemic adaptive immune tolerance. Hepatology. 2013;58:73–85. - PubMed
-
- Wang H, Wu B, Li L, Hu L, Lin J, Jiang C. Hepatic expansion of virus-specific CD8(+)BTLA(+) T cells with regulatory properties in chronic hepatitis B virus infection. Cell Immunol. 2017;311:36–45. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources