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Meta-Analysis
. 2020 Mar 1;25(2):e291-e298.
doi: 10.4317/medoral.23353.

Assessment of clinical outcomes and histomorphometric findings in alveolar ridge augmentation procedures with allogeneic bone block grafts: A systematic review and meta-analysis

F Pérez-González  1 , P Molinero-Mourelle, L Sánchez-Labrador, L-M Sáez-Alcaide, A Limones, J Cortés-Bretón Brinkmann, J López-Quiles
Affiliations
Meta-Analysis

Assessment of clinical outcomes and histomorphometric findings in alveolar ridge augmentation procedures with allogeneic bone block grafts: A systematic review and meta-analysis

F Pérez-González et al. Med Oral Patol Oral Cir Bucal. .

Abstract

Background: This systematic literature review aimed to evaluate the efficacy of allogeneic bone blocks for ridge augmentation by assessing block survival rates and subsequent implant survival, including post-surgical complications and histomorphometric analysis.

Material and methods: An electronic and manual search among references, was conducted up to April 2019 by two independent authors. Inclusion criteria were: human clinical trials in which the outcomes of allogeneic bone block grafts were evaluated by means of their survival rates and subsequent implant success rates.

Results: Seven articles fulfilled the inclusion criteria and were analyzed. A total of 323 allogeneic block grafts were monitored for a minimum of 12 months follow-up after surgery, of which thirteen (4.02%) failed. Regarding the cumulative implant survival rate, the weighted mean was 97.36%, computed from 501 implants. Histologic and histomorphometric analysis showed that allogeneic block grafts presented some clinical and microstructural differences in comparison with autologous block grafts.

Conclusions: Atrophic alveolar crest reconstruction with allogeneic bone block grafts would appear a feasible alternative to autologous bone block grafts, obtaining a low block graft failure rate, similar implant survival rate and fewer postoperative complications. Further investigations generating long term data are needed to confirm these findings.

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Conflict of interest statement

Conflicts of interest Authors do not have any conflict of interest.

Figures

Figure 1
Figure 1
Flow chart of the inclusion and exclusion of studies in this review.
Figure 2
Figure 2
Survival rates of allogenic block graft.
Figure 3
Figure 3
Survival rate of implants placed in allogeneic block graft.
See this image and copyright information in PMC

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