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. 2020 Feb 10;20(1):48.
doi: 10.1186/s12877-020-1461-z.

Prevalence and correlates of Alzheimer's disease and related dementias in rural Uganda: cross-sectional, population-based study

Vincent Mubangizi  1 , Samuel Maling  2 , Celestino Obua  2 , Alexander C Tsai  2   3
Affiliations

Prevalence and correlates of Alzheimer's disease and related dementias in rural Uganda: cross-sectional, population-based study

Vincent Mubangizi et al. BMC Geriatr. .

Abstract

Background: There is a paucity of data on the prevalence and correlates of Alzheimer's disease and related dementias in sub-Saharan Africa. The aim of the study was to estimate the prevalence and correlates of Alzheimer's disease and related dementias in rural Uganda.

Methods: We conducted a cross-sectional, population-based study in a rural region of southwestern Uganda. The Brief Community Screening Instrument for Dementia was administered to a multi-stage area probability sample of 400 people aged 60 years and over. Multivariable logistic regression was used to estimate correlates of probable dementia.

Results: Overall, 80 (20%) of the sample screened positive for dementia. On multivariable regression, we estimated the following correlates of probable dementia: age (adjusted odds ratio [AOR], 1.02 per year; 95% confidence interval [CI], 1.10-1.03, p<0.001), having some formal education (AOR, 0.57; 95% CI, 0.41-0.81, p = 0.001), exercise (AOR, 0.44; 95% CI, 0.27-0.72, p = 0.001), and having a ventilated kitchen (AOR, 0.43; (95% CI, 0.24-0.77, p = 0.001).

Conclusions: In this population-based sample of older-age adults in rural Uganda, nearly one-fifth screened positive for dementia.

Keywords: Alzheimer’s disease; Dementia; Sub-Saharan Africa; Uganda.

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Conflict of interest statement

The authors declare that they have no competing interests.

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