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Case Reports
. 2020 Winter;11(1):110-115.
doi: 10.22088/cjim.11.1.110.

Papillary carcinoma in correlation to thyroidal duct cyst: A case series

Adele Bahar  1   2 , Zhila Torabizadeh  3   4 , Marzieh Movahedi Rad  1   2 , Zahra Kashi  1   2
Affiliations
Case Reports

Papillary carcinoma in correlation to thyroidal duct cyst: A case series

Adele Bahar et al. Caspian J Intern Med. 2020 Winter.

Abstract

Background: Persistent thyroglossal duct leads to a fibrous cyst formation named thyroglossal cyst which is the most common form of congenital cyst and usually located in the midline neck below the hyoid bone. Rarely the thyroglossal cyst is associated with thyroid cancer. Although the Sistrunk procedure is often considered adequate, currently there is no clear consensus on the optimal management of thyroglossal duct cyst especially duct cyst carcinoma. In addition, there is no consensus about concurrent thyroidectomy in patients with thyroglossal cyst duct carcinoma.

Case presentation: In this article, we present four patients with thyroglossal duct cyst and papillary thyroid cancer. Papillary thyroid cancer was located into the thyroglossal duct cyst (thyroglossal duct carcinoma) in two patients and two patients had thyroglossal duct cyst with thyroid carcinoma in thyroid tissue. Cervical lymph nodes were involved in one of the three patients. Sistrunk procedure and total thyroidectomy were performed for all. The thyroid lobes were not involved in patients with thyroid duct cyst carcinoma. Tumor or thyroglossal duct cyst recurrence did not occur in any of the patients in follow-up.

Conclusion: The correlation between thyroglossal cyst and papillary thyroid carcinoma is high. In subjects with thyroglossal duct cyst, in addition to cyst assessment, thyroid gland and neck lymph nodes should be evaluated for malignancy.

Keywords: Sistrunk; Thyroglossal duct cyst; Thyroid carcinoma.

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Conflict of interest statement

This study was not a research work and was not supported by the Vice president for Research.

Figures

Figure 1
Figure 1
Papillary microcarcinoma
Figure 2
Figure 2
Cystic space containing papillary carcinoma
Figure 3
Figure 3
Papillary structures filled the thyroglossal duct cyst
Figure 4
Figure 4
Papillary microcarcinoma arising from thyroglossal duct cyst
See this image and copyright information in PMC

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