Conflicts of Interest: AA Lalani: honoraria/consulting from Bristol-Myers Squibb, Eisai, Ipsen, Janssen, Merck, Pfizer, Roche, TerSera, AbbVie, Astellas; educational grants from Novartis, Roche. SK Pal: Consultant for Astellas, Aveo, Bristol-Myers Squibb, Eisai, Exelixis, Genentech, Ipsen, Myriad, Novartis, Pfizer; honoraria from Astella, Medivation, Novartis; Research funding from Medivation. GP Sonpavde: grants from Boehringer-Ingelheim, grants from Bayer, grants from Onyx-Amgen, grants and personal fees from Pfizer, personal fees from Genentech, personal fees from Novartis, grants and personal fees from Merck, grants and personal fees from Sanofi, personal fees and other from Seattle Genetics/Astellas, personal fees from Clinical Care Options, grants, personal fees and other from Astrazeneca, personal fees from Uptodate, personal fees from Exelixis, personal fees and other from Bristol-Myers-Squibb (BMS), grants and personal fees from Janssen, personal fees from Amgen, personal fees from Eisai, personal fees from NCCN, grants from Celgene, personal fees from Physicians Education Resource, personal fees from Onclive, personal fees from Research to Practice, other from Bavarian Nordic, other from Debiopharm, other from QED Therapeutics. P Grivas: personal fees and other from Genentech, personal fees and other from Bayer, personal fees and other from Merck & Co., personal fees and other from Mirati Therapeutics, other from Oncogenex, personal fees and other from Pfizer, personal fees and other from Bristol-Myers Squibb, personal fees, non-financial support and other from Astra Zeneca, personal fees from Biocept, personal fees, non-financial support and other from ClovisOncology, personal fees from EMD Serono, personal fees from Seattle Genetics, personal fees from Foundation Medicine, personal fees from Driver Inc., personal fees from QED Therapeutics, personal fees from Heron Therapeutics, personal fees from Janssen, other from Bavarian Nordic, other from Immunomedics, other from Debiopharm, personal fees from GlaxoSmithKline, personal fees from Roche, personal fees from Genzyme, personal fees from Exelixis.