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Case Reports
. 2020 Jan 30;6(2):146-148.
doi: 10.1016/j.jdcr.2019.11.012. eCollection 2020 Feb.

Primary cicatricial alopecia associated with systemic indolent mastocytosis

Sonya Prasad  1 , Brianna De Souza  1 , Laura J Burns  1 , Maryanne M Senna  1   2
Affiliations
Case Reports

Primary cicatricial alopecia associated with systemic indolent mastocytosis

Sonya Prasad et al. JAAD Case Rep. .

Erratum in

  • Correction.
    [No authors listed] [No authors listed] JAAD Case Rep. 2020 May 22;6(6):509. doi: 10.1016/j.jdcr.2020.03.004. eCollection 2020 Jun. JAAD Case Rep. 2020. PMID: 32490111 Free PMC article.
No abstract available

Keywords: PCA, primary cicatricial alopecia; SM, systemic mastocytosis; TMEP, telangiectasia macularis eruptiva perstans; alopecia; cicatricial alopecia; mastocytosis; primary cicatricial alopecia; systemic mastocytosis; telangiectasia macularis eruptiva perstans.

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Figures

Fig 1
Fig 1
Primary cicatricial alopecia involving the right frontal and temporal aspects of the scalp.
Fig 2
Fig 2
Scalp punch biopsy showing early scarring alopecia with features of primary cicatricial alopecia. A, Superficial sections of the scalp show perifollicular fibrosis and inflammation (arrows) at the level of the isthmus/infundibulum without interface changes at the dermoepidermal junction. (Hematoxylin-eosin; original magnification: ×4.) B, Transverse sectioning shows no significant inflammation at the deep aspect of the biopsy. (Hematoxylin-eosin; original magnification: ×4.) C, A compound follicle with perifollicular fibrosis and inflammation shown at higher power. (Hematoxylin-eosin; original magnification: ×20.) D, Immunohistochemical staining for CD117 highlights mast cells with spindled morphology (arrows) in the area of scarring, compatible with involvement by the patient's underlying mastocytosis. (CD117 stain; original magnification: ×20.)
Fig 3
Fig 3
Clinical presentation of telangiectasia macularis eruptiva perstans involving the anterior aspect of the left knee.
See this image and copyright information in PMC

References

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    1. Anzai A., Wang E.H., Lee E.Y., Aoki V., Christiano A.M. Pathomechanisms of immune-mediated alopecia. Int Immunol. 2019;31(7):439–447. - PMC - PubMed

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