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Case Reports
. 2020 Jan 18:32:100537.
doi: 10.1016/j.gore.2020.100537. eCollection 2020 May.

Case report of a paraganglioma arising from a mature cystic teratoma of the ovary

Jennifer Haag  1 , Lakotah Hardie  2 , Amber Berning  3 , Lauren Fishbein  4 , Bradley R Corr  5
Affiliations
Case Reports

Case report of a paraganglioma arising from a mature cystic teratoma of the ovary

Jennifer Haag et al. Gynecol Oncol Rep. .

Abstract

Paragangliomas are rare neuroendocrine neoplasms derived from sympathetic or parasympathetic paraganglia and have the ability to secrete catecholamines. We present the case of a 37-year-old asymptomatic female who underwent right ovarian cystectomy for a mature cystic teratoma and was found to have an intra-tumoral paraganglioma. More research is needed to determine metastatic potential as well as the likelihood of recurrence of these unique neoplasms.

Keywords: Mature cystic teratoma; Neuroendocrine neoplasm; Paraganglioma.

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Conflict of interest statement

The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper.

Figures

Fig. 1
Fig. 1
Mature cystic teratoma demonstrating three germ layers including intratumoral paraganglioma (H&E, 2×) (Fig. 1A). Higher-power view of intratumoral paraganglioma demonstrating characteristic nested architecture (H&E, 10×) (Fig. 1B). Patchy chromogranin positivity (10×) (Fig. 1C). Diffuse synaptophysin positivity (10×) (Fig. 1D). Sox 10 highlighting scattered sustentacular cells (10×) (Fig. 1E).
See this image and copyright information in PMC

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