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. 1988 Sep-Oct;51(5):845-50.
doi: 10.1021/np50059a005.

Antitumor principles in mosses: the first isolation and identification of maytansinoids, including a novel 15-methoxyansamitocin P-3

K Sakai  1 , T Ichikawa, K Yamada, M Yamashita, M Tanimoto, A Hikita, Y Ijuin, K Kondo
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Antitumor principles in mosses: the first isolation and identification of maytansinoids, including a novel 15-methoxyansamitocin P-3

K Sakai et al. J Nat Prod. 1988 Sep-Oct.

Abstract

A novel 15-methoxyansamitocin P-3 [2], in company with three known maytansinoids 1, 3, and 4, was isolated for the first time from two Japanese mosses, Isothecium subdiversiforme and Thamnobryum sandei. All are potent cytotoxic compounds.

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